The report details Mikoyan's talks with President John F. Kennedy in Washington D.C. Among the topics of discussion were questions of hemispheres of influence, whether the Soviet Union promoted a revolution against the USA in Cuba, and whether Castro was made an enemy of the USA or was one from the beginning. Conduct of both nations with regards to the Cuban question is discussed at length, ranging from whether U.S. was correct in acting against a perceived threat to security, the conduct of the Cuban people, the extent of Soviet involvement in Cuba, and what military hardware would be left in Cuba after the removal of the nuclear missile bases.

In this conversation between Khrushchev and Novotny, Khrushchev used exceptionally candid language to defend his handling of the superpower confrontation, what he described as “six days which shook the world.” While well aware that many fellow communists (including the Chinese and Cubans) regarded his agreement under pressure from US President John F. Kennedy to remove the missiles as a surrender to the imperialists, Khrushchev stoutly defended his action as not only a necessary measure to avoid a catastrophic nuclear war, but actually a victory. Khrushchev bluntly criticized Fidel Castro for failing to comprehend the true nature of war in the thermonuclear age and, that at the height of the crisis, he had suggested in a letter to Khrushchev that the Soviets should be the first to use nuclear weapons, striking the United States should it attack Cuba, even though this would lead promptly to a global war.

This cable sent to Prague confirms the decision by President John F. Kennedy to blockade Cuba, based on talks between Cuban Foreign Minister Raul Roa and Soviet Ambassador to Cuba Aleksandr Alekseev. Despite no orders for the American warships to stop Soviet ships, Alekseev was preparing in anticipation for "dangerous provocations." Cuba canceled all PanAm flights, while at the same time allowing Czech and Soviet flights to proceed.